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Research Article |

Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains

The aim of this work is to assess the antimicrobial potential of cassia occidentalis flax (Caesalpiniaceae) leaf extracts on drug-resistant microbial strains, in order to bring phytotherapeutic prescriptions into line with the potential biological activities of the chemical constituents present. Aqueous and hydro-ethanolic extracts were prepared according to the methods of Zirihi and Kra (2003). The antimicrobial activities were determined by measuring the rate of inhibition of microbial growth, diffusion on a solid medium and dilution in a liquid medium. In addition, the mode of action of the active extracts was determined by the ratio of the minimum fungicidal concentration to the minimum inhibitory concentration (MFC/MIC). Aqueous and hydroalcoholic extracts from the leaves of C. occidentalis have been shown to have antimicrobial activity. These extracts inhibited the proliferation of C. albicans strains resistant to nystatin. The activity of the aqueous extracts was similar to that obtained with the hydroalcoholic extracts. However, both types of extract showed no significant efficacy against S. aureus, E. coli and K. pneumoniae strains at the doses used (200 mg/ml; 100 mg/ml and 50 mg/ml) in all the pharmacological tests repeated during this study.

Pharmaco-Multi-Resistance, Antimicrobial Activity, Fungicide, Cassia Occidentatlis

APA Style

Ngassaki, R., Ampa, R., Tchiyamba, P. L., Assiana, D. O. E., Ahombo, G. (2024). Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains. International Journal of Microbiology and Biotechnology, 9(1), 1-6.

ACS Style

Ngassaki, R.; Ampa, R.; Tchiyamba, P. L.; Assiana, D. O. E.; Ahombo, G. Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains. Int. J. Microbiol. Biotechnol. 2024, 9(1), 1-6. doi: 10.11648/j.ijmb.20240901.11

AMA Style

Ngassaki R, Ampa R, Tchiyamba PL, Assiana DOE, Ahombo G. Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains. Int J Microbiol Biotechnol. 2024;9(1):1-6. doi: 10.11648/j.ijmb.20240901.11

Copyright © 2024 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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